VISDB Viral Integration Site DataBase

VIS ID

TVIS20005060

Fusion event

HPV-MYC integration

Validated

Yes

Detection method

RNA-Seq+RT-PCR

Data source

Curated

Sample type

Disease

Neuroendocrine carcinoma (NC)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HPV

Subtype

HPV18

Reference genome

Not given

Chromosome

chr8

Cytoband

q24.21

Reference genome

Start

End

128806935/127794689 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-let-7a-5p ; hsa-let-7g-5p ; hsa-mir-34a-5p ; hsa-mir-98-5p ; hsa-let-7c-5p ; hsa-mir-26a-5p ; hsa-mir-145-5p ; hsa-mir-21-5p ; hsa-mir-34b-5p ; hsa-mir-34c-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-34b-3p ; hsa-mir-378a-3p ; hsa-mir-371a-3p ; hsa-mir-373-3p ; hsa-mir-451a ; hsa-mir-33b-5p ; hsa-mir-135a-5p ; hsa-mir-449c-5p ; hsa-mir-429 ; hsa-mir-335-5p ; hsa-let-7f-5p ; hsa-mir-320b ; hsa-mir-744-5p ; hsa-mir-423-5p ; hsa-mir-320a ; hsa-let-7b-5p ; hsa-mir-148a-3p ; hsa-mir-212-3p ; hsa-mir-494-3p ; hsa-mir-155-5p ; hsa-mir-33a-5p ; hsa-mir-1294 ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-30e-3p ; hsa-mir-323a-3p ; hsa-mir-449a ; hsa-mir-940 ; hsa-mir-1304-5p ; hsa-mir-1827 ; hsa-mir-2682-5p ; hsa-mir-548au-3p ; hsa-mir-8074 ; hsa-mir-4426 ; hsa-mir-4647 ; hsa-mir-4662b ; hsa-mir-4289 ; hsa-mir-16-2-3p ; hsa-mir-195-3p ; hsa-mir-5197-5p ; hsa-mir-6507-3p ; hsa-mir-487b-3p ; hsa-mir-7-5p ; hsa-mir-93-5p ; hsa-mir-324-3p ; hsa-mir-184 ; hsa-mir-126-5p ; hsa-mir-25-3p ; hsa-mir-92a-2-5p ; hsa-mir-92a-1-5p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-3p ; hsa-mir-106b-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-516a-5p ; hsa-mir-455-3p ; hsa-mir-4677-3p ; hsa-mir-4510 ; hsa-mir-375 ; hsa-mir-3159 ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-23a-3p ; hsa-mir-222-3p ; hsa-mir-196b-5p ; hsa-mir-196a-5p ; hsa-mir-16-5p ; hsa-mir-151a-5p ; hsa-mir-148a-5p ; hsa-mir-125a-3p ; hsa-mir-125a-5p ; hsa-mir-1248 ; hsa-let-7i-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-mir-302a-5p ; hsa-mir-3919 ; hsa-mir-4699-3p ; hsa-mir-4797-5p ; hsa-mir-6765-5p ; hsa-mir-622 ; hsa-mir-135b-5p ; hsa-mir-889-5p ; hsa-mir-4668-5p ; hsa-mir-4762-5p ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-130a-3p ; hsa-mir-25-5p ; hsa-mir-185-5p ; hsa-mir-29a-3p ; hsa-mir-561-3p ; hsa-mir-34a-3p ; hsa-mir-599 ; hsa-mir-29b-3p ; hsa-mir-129-2-3p ; hsa-mir-3157-5p ; hsa-mir-377-5p ; hsa-mir-4316 ; hsa-mir-4432 ; hsa-mir-4691-3p ; hsa-mir-512-5p ; hsa-mir-513c-5p ; hsa-mir-514b-5p ; hsa-mir-586 ; hsa-mir-6086 ; hsa-mir-655-5p

Nearest miRNA

hsa-mir-12123/Upstream/2908663; hsa-mir-10400/Downstream/1273;

Nearest TSS

Nearest CpG islands

chr8-CpG: 17/Target, None/Upstream, None/Downstream

Nearby gene

POU5F1B ; PVT1(+) ;

Nearest cancer related gene

MYC(OG, No orient, 0)

Upstream sequence

CACAGGTTCAAAATTTATAGTAAAATAAGCATCAAAAAAAAACTACAATTTAGCTGGCCTCACTGCCTCTGCCCTCAGTGAGCTGGCGACCAAATTCTAA

Downstream sequence

GGCGGTCCCTGTGACCTGTGGAGACACGGCCAGATCTGCCCTCCAGTAAGTTCCAATTTTGTCCCCTGCGTTTCTGGAAACTCTCGAGACTTGGCCCTGA