Basic Information
VIS ID
TVIS20005061
Fusion event
HPV-chr8:p11.23 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
37550966/37693448 (Hg38)
End
37552221/37694703 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/7736100; hsa-mir-10400/Downstream/3576345;
Nearest TSS
ENST00000518652/Upstream/19061; ENST00000331569/Downstream/1048;
Nearest CpG islands
chr8-CpG: 351/Target, None/Upstream, None/Downstream
Nearby gene
KCNU1 ; ZNF703(+) ;
Nearest cancer related gene
ZNF703(OG, +) ;
Upstream sequence
gtctgtcttcctctactactaggcaagaaccatgtccttttcactattttatgtccagtgcccagAGAAATAGGATGTAATATAAAATTCATCATCTAAA
Downstream sequence
AGCAATGCACACTGTATCAGAAAGGCGCAGGGAGTCGGGAAGGGTATTGTTATTTTTAATTAAAAGTTTTTATCCCGAAATTTGCCTGGGGAAAGCAAGT
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate