Basic Information
VIS ID
TVIS20005063
Fusion event
HPV-KRT39 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Adenocarcinoma (AC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
39101544/40945292 (Hg38)
End
39132008/40975756 (Hg38)
Location type
Intronic
Target gene
KRT39
Nearest miRNA
hsa-mir-1180/Upstream/751629; hsa-mir-10226/Downstream/541408;
Nearest TSS
ENST00000595228/Upstream/7658; ENST00000621138/Downstream/8552;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/81443, chr17-CpG: 83/Downstream/551900
Nearby gene
KRT23 ; KRT40(+) ;
Upstream sequence
tttgggcactggacagacttgctgggtgcagggaagctcacttcctctctggatgccaacttccttatctgcagaatgggcttaggtgtgctcagtggag
Downstream sequence
tagtgtaactggatgtttgtaacaccaaagatacatgcttgaggggatggacaccccattctccatgtgattattacacattgcatgcctgtgtcaaatc
Target sequence
tcttgatctgttgcccaggctggagtgcactggcgccatctcagctcactgcagtctccaccccccaggttcaagcctcccgagcagctgggattacaggcgcccaccaccatgccctgctattttttgtattttttgtagagatggggtttcaccatgttggccaggctggtctcaaactcctgaccttgaaagatctgcttggctcagcttcccaaagtgttgagattacaggcgcgagccactgcatgcggc
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate