VISDB Viral Integration Site DataBase

VIS ID

TVIS20005076

Fusion event

HPV-P4HB integration

Validated

Yes

Detection method

RNA-Seq+RT-PCR

Data source

Curated

Sample type

Disease

Squamous-cell carcinoma (SCC)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HPV

Subtype

HPV16

Reference genome

Chromosome

chr17

Cytoband

q25.3

Reference genome

Start

End

79821123/81863247 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-210-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-183-5p ; hsa-mir-92a-3p ; hsa-mir-188-5p ; hsa-mir-3672 ; hsa-mir-4520-3p ; hsa-mir-6516-3p ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4638-3p ; hsa-mir-518c-5p ; hsa-mir-451b ; hsa-mir-514a-5p ; hsa-mir-548n ; hsa-mir-1252-5p ; hsa-mir-1294 ; hsa-mir-135b-3p ; hsa-mir-298 ; hsa-mir-3650 ; hsa-mir-3919 ; hsa-mir-4292 ; hsa-mir-4308 ; hsa-mir-4710 ; hsa-mir-4756-3p ; hsa-mir-4787-5p ; hsa-mir-483-5p ; hsa-mir-548e-5p ; hsa-mir-597-5p ; hsa-mir-6077 ; hsa-mir-6134 ; hsa-mir-642b-5p ; hsa-mir-668-3p ; hsa-mir-670-5p ; hsa-mir-6752-5p ; hsa-mir-6758-5p ; hsa-mir-6782-5p ; hsa-mir-6791-5p ; hsa-mir-6842-5p ; hsa-mir-6856-5p ; hsa-mir-7110-5p ; hsa-mir-7854-3p ; hsa-mir-887-3p

Nearest miRNA

hsa-mir-10226/Upstream/153478; hsa-mir-4525/Downstream/373421;

Nearest TSS

Nearest CpG islands

chr17-CpG: 147/Target, None/Upstream, None/Downstream

Nearby gene

PPP1R27 ; ARHGDIA(+) ;

Upstream sequence

CGAGTGCTCTAATGAGCACACACAAGGCAGCAGGTGGGAGCCTCACACTGGCAAGCCTGGACCTCTGCTCACACCCGCAAACCAACTGAATCTCTCACTC

Downstream sequence

TCAGTCAGCGGCATAAGTTGTACCTGCTGGGAGAACTGTCTGCTTCCTCCGGGTGACTTTTCTGGCCAAGAAGGAATATGAGTATGTGCCTCCCTGAGCA

Target sequence

tgacatatctctgcactgatcacccaggtgatgtaacccttgtctaggctctgccaaaagggggcattgtgacataactctgcactgatcacccaggtgatgggactcttgtctaggctctgcctacaggggcattgtgacatatctctgcagtgatcacgcaggtgatgtaactcttgtctatatctgtctactggtggcattgtggcatatttctgcactgatcacccaggtgatggactcttgtcttggatc