Basic Information
VIS ID
TVIS20005079
Fusion event
HPV-chr7:q36.1 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Adenocarcinoma (AC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
148885555/149188463 (Hg38)
End
148886074/149188982 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/1810342; hsa-mir-153-2/Downstream/2049439;
Nearest TSS
ENST00000635602/Upstream/40060; ENST00000462740/Downstream/6503;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/39999, chr7-CpG: 98/Downstream/6350
Nearby gene
ZNF398 ; ZNF282(+) ;
Upstream sequence
GAACATCTTTCCAAACCCCATTGCTGACCTTGTCCTTGACTGATTCCTCACATTGCAATGGGTGCTATACCTACACAGGAAAGGACTAATGAGCTATAGC
Downstream sequence
gacggagtctcactctgtggaccaggctggagtgcactggcgcgatcttggctcactgcaagctccgcctttcgggtttgcgtcattctctgcctcagcc
Target sequence
agagttcccccaagtggttttaatgtgcctgcaaggtacagaaGATCAGAGAAAGTGAATTATTGGACTGGAAATGGCTACTTAGCCTGCTTTACTGGAGCAGGGAGCTGTGGATTGGAGATTAATAAAGGGTCTTTGAATCCACAATGGGAAGTCATAATTTGATTCTAGAAGCAGGACTCAGAAGGATATAAAGCTATGGGAATGGTGGTTGAAAAAGTTCTGACCTCAATAGTTAGGAGCTCTAGAGTCAGT
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate