Basic Information
VIS ID
TVIS20005080
Fusion event
HPV-TBL1XR1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Adenocarcinoma (AC)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.32
Reference genome
End
176754943/177037155 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-122-5p ; hsa-mir-21-5p ; hsa-mir-30c-5p ; hsa-mir-548c-3p ; hsa-mir-5691 ; hsa-mir-6805-3p ; hsa-mir-4433b-5p ; hsa-mir-4427 ; hsa-mir-506-5p ; hsa-mir-3613-3p ; hsa-mir-5003-5p ; hsa-mir-4668-5p ; hsa-mir-625-5p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-3148 ; hsa-mir-6770-5p ; hsa-mir-3179 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-3154 ; hsa-mir-4314 ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6827-5p ; hsa-mir-505-5p ; hsa-mir-3194-3p ; hsa-mir-767-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3192-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-1277-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-511-5p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-6509-3p ; hsa-mir-4711-3p ; hsa-mir-6830-3p ; hsa-mir-627-3p ; hsa-mir-4742-3p ; hsa-mir-4509 ; hsa-mir-4744 ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-181c-3p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-550b-2-5p ; hsa-mir-4684-5p ; hsa-mir-6886-3p ; hsa-mir-938 ; hsa-mir-942-5p ; hsa-mir-554 ; hsa-mir-5088-3p ; hsa-mir-5579-5p ; hsa-mir-382-5p ; hsa-mir-7150 ; hsa-mir-4433a-5p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-6834-3p ; hsa-mir-186-3p ; hsa-mir-4448 ; hsa-mir-7110-3p ; hsa-mir-6758-3p ; hsa-mir-7705 ; hsa-mir-1278 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p
Nearest miRNA
hsa-let-7g/Upstream/509023; hsa-mir-1224/Downstream/6849645;
Upstream sequence
GTGGAACTTGACTCATAAAGGCGAGAGACTTGACTATTGAAAAAGGTCTCCTATGAAATCTGAatttcacttaatcctcagaacaactgttgagggggtt
Downstream sequence
ataccacagcaaaatcaaattaatacaACGCAAAGAATTCCAATCAAATCCATGAATGCTACAAAGATTTTGAGTACTTATTAAGTCAAATCTTTACATA
Target sequence
ATCAGAGCAGCAGGAAGAAGGTTAGTGCAATTATACTTTCATTAAAAAAAATTCTGAATCACTGCTATTTAAAAACACCTTGAAGCAAGTCTTTTGTTTGAGATTGTTTTTTAAACTAAGGTAGCAAACATTTTGCCATGTAATGGCAGTGTTATATGCCGTTATCTTGCTTTGTATAAAGAAAACAACATGAGAGATTTTTAATACTGGAGTTTGGTTACATTACATATTTAAGCTTCTACACAGAATGATGGA
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate