Basic Information
VIS ID
TVIS20005082
Fusion event
HPV-TMCC3 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Adenosquamous carcinoma (ASC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q22
Reference genome
GRCh37/hg19
Start
94976090/94582314 (Hg38)
End
95049742/94655966 (Hg38)
Location type
Intronic
Target gene
TMCC3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-6864-5p ; hsa-mir-6126 ; hsa-mir-4493 ; hsa-mir-605-3p ; hsa-mir-4635 ; hsa-mir-4511 ; hsa-mir-3133 ; hsa-mir-548x-3p ; hsa-mir-5582-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac
Nearest miRNA
hsa-let-7i/Upstream/10962; hsa-mir-1178/Downstream/178432;
Nearest TSS
ENST00000382841/Upstream/85872; ENST00000551792/Downstream/268840;
Nearest CpG islands
chr12-CpG: 90/Target, None/Upstream, None/Downstream
Nearby gene
CEP83 ; KRT19P2(+) ;
Upstream sequence
cagccagtgcattcttttccactactatgcaccattccaatacacactagtggaacttttaacaactagactaccattttgtaccagAGTCTATCTGTAC
Downstream sequence
tagagcactagatccagcATTTTCCATCTGctatcgctgcatgacaaaccaccttaaaatgctttggcttggccaggtgcagtggctcacgcctgtaatc
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate