VISDB Viral Integration Site DataBase

VIS ID

TVIS20005086

Fusion event

HPV-chr14:q21.2 integration

Validated

Yes

Detection method

RNA-Seq+RT-PCR

Data source

Curated

Sample type

Disease

Squamous-cell carcinoma (SCC)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HPV

Subtype

HPV18

Reference genome

Not given

Chromosome

chr14

Cytoband

q21.2

Reference genome

Start

End

45499251/45030048 (Hg38)

Location type

Intronic

Target gene

KLHL28 ; TOGARAM1

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-361-5p ; hsa-mir-130b-3p ; hsa-mir-29c-3p ; hsa-mir-30b-5p ; hsa-mir-93-5p ; hsa-mir-369-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-376a-5p ; hsa-mir-489-3p ; hsa-mir-4764-5p ; hsa-mir-1243 ; hsa-mir-6803-5p ; hsa-mir-3688-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4525 ; hsa-mir-5010-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-4668-5p ; hsa-mir-625-5p ; hsa-mir-4470 ; hsa-mir-3148 ; hsa-mir-298 ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-622 ; hsa-mir-4264 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-20b-5p ; hsa-mir-182-5p ; hsa-mir-3658 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-3653-3p ; hsa-mir-5584-5p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-6083 ; hsa-let-7c-3p ; hsa-mir-4473 ; hsa-mir-155-5p ; hsa-mir-3135a ; hsa-mir-203a-3p ; hsa-mir-6080 ; hsa-mir-3973 ; hsa-mir-5680 ; hsa-mir-5700 ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-448 ; hsa-mir-136-3p ; hsa-mir-1295b-3p ; hsa-mir-4760-3p ; hsa-mir-3910 ; hsa-mir-3714 ; hsa-mir-124-3p ; hsa-mir-506-3p ; hsa-mir-6505-5p ; hsa-mir-6720-5p ; hsa-mir-4735-5p ; hsa-mir-6512-3p ; hsa-mir-6849-3p ; hsa-mir-5586-5p ; hsa-mir-5580-3p ; hsa-mir-6832-3p ; hsa-mir-130b-5p ; hsa-mir-1264 ; hsa-mir-4797-3p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-6794-3p ; hsa-mir-3671 ; hsa-mir-630 ; hsa-mir-627-3p ; hsa-mir-4639-3p ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-5003-3p

Nearest miRNA

hsa-mir-208a/Upstream/7982165; hsa-mir-1185-1/Downstream/2730947;

Nearest TSS

Nearest CpG islands

chr14-CpG: 33/Target, None/Upstream, None/Downstream

Nearby gene

PRPF39 ; C14orf28(+) ;

Upstream sequence

AAAAGATTGTCTTGTGTTTACTTCTTTTTTAATTCTCTCATTGTCTTCAGTTGATATTCCTCTCAGATGCCAGATACCTGTCATTGTTGCCAGATGACTG

Downstream sequence

tgacctcgtgatctgctcacctcagcctcccagaatgctgggattacaggtgtgagccaccatgcccagccAACAGTGGAAGTTTTTAAAAAAAAAAATC