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TVIS20005087
Basic Information
VIS ID
TVIS20005087
Fusion event
HPV-chr14:q21.2 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
45408708/44939505 (Hg38)
End
45499175/45029972 (Hg38)
Location type
Intronic
Target gene
KLHL28
;
TOGARAM1
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-361-5p
;
hsa-mir-130b-3p
;
hsa-mir-29c-3p
;
hsa-mir-30b-5p
;
hsa-mir-93-5p
;
hsa-mir-369-3p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-376a-5p
;
hsa-mir-489-3p
;
hsa-mir-4764-5p
;
hsa-mir-1243
;
hsa-mir-6803-5p
;
hsa-mir-3688-5p
;
hsa-mir-6751-5p
;
hsa-mir-7109-5p
;
hsa-mir-4665-5p
;
hsa-mir-1275
;
hsa-mir-4525
;
hsa-mir-5010-5p
;
hsa-mir-7111-5p
;
hsa-mir-6870-5p
;
hsa-mir-5698
;
hsa-mir-4723-5p
;
hsa-mir-4668-5p
;
hsa-mir-625-5p
;
hsa-mir-4470
;
hsa-mir-3148
;
hsa-mir-298
;
hsa-mir-6774-5p
;
hsa-mir-635
;
hsa-mir-622
;
hsa-mir-4264
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-106a-5p
;
hsa-mir-17-5p
;
hsa-mir-519d-3p
;
hsa-mir-526b-3p
;
hsa-mir-20b-5p
;
hsa-mir-182-5p
;
hsa-mir-3658
;
hsa-mir-524-5p
;
hsa-mir-520d-5p
;
hsa-mir-3653-3p
;
hsa-mir-5584-5p
;
hsa-mir-4652-3p
;
hsa-mir-4743-3p
;
hsa-mir-6083
;
hsa-let-7c-3p
;
hsa-mir-4473
;
hsa-mir-155-5p
;
hsa-mir-3135a
;
hsa-mir-203a-3p
;
hsa-mir-6080
;
hsa-mir-3973
;
hsa-mir-5680
;
hsa-mir-5700
;
hsa-mir-559
;
hsa-mir-548y
;
hsa-mir-548w
;
hsa-mir-548o-5p
;
hsa-mir-548j-5p
;
hsa-mir-548i
;
hsa-mir-548h-5p
;
hsa-mir-548d-5p
;
hsa-mir-548c-5p
;
hsa-mir-548bb-5p
;
hsa-mir-548b-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548au-5p
;
hsa-mir-548as-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548am-5p
;
hsa-mir-548ak
;
hsa-mir-548ae-5p
;
hsa-mir-548ad-5p
;
hsa-mir-548ab
;
hsa-mir-548a-5p
;
hsa-mir-520f-3p
;
hsa-mir-302c-3p
;
hsa-mir-448
;
hsa-mir-136-3p
;
hsa-mir-1295b-3p
;
hsa-mir-4760-3p
;
hsa-mir-3910
;
hsa-mir-3714
;
hsa-mir-124-3p
;
hsa-mir-506-3p
;
hsa-mir-6505-5p
;
hsa-mir-6720-5p
;
hsa-mir-4735-5p
;
hsa-mir-6512-3p
;
hsa-mir-6849-3p
;
hsa-mir-5586-5p
;
hsa-mir-5580-3p
;
hsa-mir-6832-3p
;
hsa-mir-130b-5p
;
hsa-mir-1264
;
hsa-mir-4797-3p
;
hsa-mir-1305
;
hsa-mir-607
;
hsa-mir-6794-3p
;
hsa-mir-3671
;
hsa-mir-630
;
hsa-mir-627-3p
;
hsa-mir-4639-3p
;
hsa-mir-7853-5p
;
hsa-mir-105-5p
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-4753-3p
;
hsa-mir-5003-3p
Nearest miRNA
hsa-mir-208a/Upstream/7987114; hsa-mir-1185-1/Downstream/2731023;
Nearest TSS
ENST00000550708/Upstream/27642;
ENST00000556823/Downstream/12336;
Nearest CpG islands
chr14-CpG: 33/Target
, None/Upstream, None/Downstream
Upstream sequence
TATACTTTTTGGTCTAAAACGCATATTCCAAATTCATAGCGAGGAATGTTTAGGGGTGCCAAACCAATCCAAGAGTCATTCTGAGGAAAGTACATCTCCA
Downstream sequence
caccatgtcaggctaatttttgtatttttagtcaagacggggtttcaccatgttggacaggctggtctcgaactcctgacctcgtgatctgctcacctca
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Sample Information
×
Sample name
SGCX-NOR-059
Sample type
Tumor
Age
41
Gender
Female
CpG Island Information
×
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