Basic Information
VIS ID
TVIS20005087
Fusion event
HPV-chr14:q21.2 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.2
Reference genome
End
45499175/45029972 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-361-5p ; hsa-mir-130b-3p ; hsa-mir-29c-3p ; hsa-mir-30b-5p ; hsa-mir-93-5p ; hsa-mir-369-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-376a-5p ; hsa-mir-489-3p ; hsa-mir-4764-5p ; hsa-mir-1243 ; hsa-mir-6803-5p ; hsa-mir-3688-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4525 ; hsa-mir-5010-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-4668-5p ; hsa-mir-625-5p ; hsa-mir-4470 ; hsa-mir-3148 ; hsa-mir-298 ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-622 ; hsa-mir-4264 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-20b-5p ; hsa-mir-182-5p ; hsa-mir-3658 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-3653-3p ; hsa-mir-5584-5p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-6083 ; hsa-let-7c-3p ; hsa-mir-4473 ; hsa-mir-155-5p ; hsa-mir-3135a ; hsa-mir-203a-3p ; hsa-mir-6080 ; hsa-mir-3973 ; hsa-mir-5680 ; hsa-mir-5700 ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-448 ; hsa-mir-136-3p ; hsa-mir-1295b-3p ; hsa-mir-4760-3p ; hsa-mir-3910 ; hsa-mir-3714 ; hsa-mir-124-3p ; hsa-mir-506-3p ; hsa-mir-6505-5p ; hsa-mir-6720-5p ; hsa-mir-4735-5p ; hsa-mir-6512-3p ; hsa-mir-6849-3p ; hsa-mir-5586-5p ; hsa-mir-5580-3p ; hsa-mir-6832-3p ; hsa-mir-130b-5p ; hsa-mir-1264 ; hsa-mir-4797-3p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-6794-3p ; hsa-mir-3671 ; hsa-mir-630 ; hsa-mir-627-3p ; hsa-mir-4639-3p ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-5003-3p
Nearest miRNA
hsa-mir-208a/Upstream/7987114; hsa-mir-1185-1/Downstream/2731023;
Nearest CpG islands
chr14-CpG: 33/Target, None/Upstream, None/Downstream
Upstream sequence
TATACTTTTTGGTCTAAAACGCATATTCCAAATTCATAGCGAGGAATGTTTAGGGGTGCCAAACCAATCCAAGAGTCATTCTGAGGAAAGTACATCTCCA
Downstream sequence
caccatgtcaggctaatttttgtatttttagtcaagacggggtttcaccatgttggacaggctggtctcgaactcctgacctcgtgatctgctcacctca
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate