Basic Information
VIS ID
TVIS20005089
Fusion event
HPV-chr12:q12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
HQ644271.1
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
GRCh37/hg19
Start
41556195/41162393 (Hg38)
End
41580912/41187110 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/15288314; hsa-let-7i/Downstream/1136590;
Nearest TSS
ENST00000382841/Upstream/133279; ENST00000402685/Downstream/1338;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/469093, chr12-CpG: 91/Downstream/1243
Upstream sequence
ctttttgcccaggctagaataaagtgacttgatcttggcttactgcaacctccgcccctcaggttcaagtgattctcctgcctcagcctcctgagtagct
Downstream sequence
AGCTCCAAGGATTTAAAAGACAAAGTCTGGAGCTGTTCTCATCAATTCCAACTGATGCCATTTGGTGTCATAGAGAATTACAAGCTTTCCAGGAACAAGG
Target sequence
TATTATGCTTTATCAGGGACACTGGTTTGATTTTCTTTATTTTAGGAAGCACTGTCACCTCCTTCTTTAAAACATTTTTACTATTTTAAAATTTGCACTGTATATTTTTCTAAGCTGTGTGGTTAACAAAGCAGTACAAATTAATTTGTAAAGTACCAACGGGTTATATAAACATTTGAACACAGACATCGTCTTCTGATAGGGTCGATGACGTATGTGGTCGCCCTGATGCTATTTACACAATGCTCTAGAGAA
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate