Basic Information
VIS ID
TVIS20005096
Fusion event
HPV-EGFL7 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Adenocarcinoma (AC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
139543325/136648873 (Hg38)
End
139562753/136668301 (Hg38)
Location type
Intronic
Target gene
EGFL7
miRNAs that regulate target gene
hsa-mir-126-3p ; hsa-mir-133a-3p ; hsa-mir-361-5p
Nearest miRNA
hsa-let-7a-1/Upstream/102614; hsa-mir-126/Downstream/2301;
Nearest TSS
ENST00000422679/Upstream/31692; ENST00000371692/Downstream/9079;
Nearest CpG islands
chr9-CpG: 21/Target, None/Upstream, None/Downstream
Nearby gene
NOTCH1 ; AGPAT2(+) ;
Upstream sequence
ACTGTTCATGAGAAACCACTGTTTTAAATATGAAGTTCAGCCTTCTTGGTCAAAAGCAAACACCACATTGGAACTTAGAAGGTTAAAATATAATGCTTTA
Downstream sequence
TGCTGCTGATGTGGCTTCTGGTGTTGGCAGTGGGCGGCACAGAGCACGCCTACCGGCCCGGGTGAGCCAAGCCCTAGCCTGGGAGTGCTGGGGTGGGGGG
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate