Basic Information
VIS ID
TVIS20005099
Fusion event
HPV-MAFA integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Adenocarcinoma (AC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
144502066/143419896 (Hg38)
End
144510443/143428273 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
MAFA
Nearest miRNA
hsa-mir-1204/Upstream/1243478; hsa-mir-10400/Downstream/304810;
Nearest TSS
ENST00000518652/Upstream/2217; ENST00000517300/Downstream/1625;
Nearest CpG islands
chr8-CpG: 40/Target, None/Upstream, None/Downstream
Nearby gene
RHPN1 ; ZC3H3(+) ;
Nearest cancer related gene
MAFA(OG, No orient, 0)
Upstream sequence
tgacatgattttagtttttttgaatgttttaagacttgttttgtggcctgacatatagtctatctttgaaaatgatccagttgttgaaagaagaatgtgt
Downstream sequence
CGCCTGGCCCAGCCTACAGGGCCTGGAGCACCCGCCTCCTCGCCCTCTCTCCCGGCTAGTCCAAAGAGCGACGAAGCATTAAAGAAAGATTCCACAAACA
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate