Basic Information
VIS ID
TVIS20005100
Fusion event
HPV-chr8:q24.3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Adenocarcinoma (AC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
144501850/143419680 (Hg38)
End
144502166/143419996 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA8D
Nearest miRNA
hsa-mir-1204/Upstream/1243262; hsa-mir-10400/Downstream/313087;
Nearest TSS
ENST00000518652/Upstream/2001; ENST00000517300/Downstream/9902;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/11888, chr8-CpG: 40/Downstream/1254
Nearby gene
MAFA-AS1(-530) ; MAFA(+8380) ;
Nearest cancer related gene
MAFA(OG, +8380) ;
Upstream sequence
aaaacaagtttattttcctatcacataaaTGTCCTAATACAATGATTAGCATTTTTATATTATAGATGTTGAAACGAATACTAATAATTTCAATGAATCA
Downstream sequence
GGATGGCAGCTCTGGGTGCCCCTCCCATGCCTGCTCCTTCCCTGCTCCCCTCCTGCCAGGAGCCAAGCTCTGTTCCCCCAGGCCCCTCTGCAAGCCCCAC
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate