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TVIS20005102
Basic Information
VIS ID
TVIS20005102
Fusion event
HPV-chr17:q12 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
HQ644271.1
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
37850235/39693982 (Hg38)
End
37895008/39738755 (Hg38)
Location type
Intronic
Target gene
ERBB2
;
GRB7
;
MIEN1
miRNAs that regulate target gene
hsa-mir-559
;
hsa-mir-548d-3p
;
hsa-mir-125b-5p
;
hsa-mir-21-5p
;
hsa-mir-125a-5p
;
hsa-mir-331-3p
;
hsa-mir-205-5p
;
hsa-mir-199b-5p
;
hsa-mir-199a-5p
;
hsa-mir-335-5p
;
hsa-mir-124-3p
;
hsa-mir-26b-5p
;
hsa-mir-326
;
hsa-mir-221-3p
;
hsa-let-7b-5p
;
hsa-mir-375
;
hsa-mir-25-3p
;
hsa-mir-670-3p
;
hsa-mir-4326
;
hsa-mir-552-3p
;
hsa-mir-541-3p
;
hsa-mir-498
;
hsa-mir-323b-5p
;
hsa-mir-193a-5p
;
hsa-mir-193a-3p
;
hsa-mir-134-5p
;
hsa-mir-6739-3p
;
hsa-mir-4677-5p
;
hsa-mir-7156-5p
;
hsa-mir-4273
;
hsa-mir-7109-5p
;
hsa-mir-4790-5p
;
hsa-mir-6868-3p
;
hsa-mir-3127-5p
;
hsa-mir-22-5p
;
hsa-mir-2116-5p
;
hsa-mir-593-3p
;
hsa-mir-6885-5p
;
hsa-mir-328-5p
;
hsa-mir-6887-5p
;
hsa-mir-486-3p
;
hsa-mir-6795-5p
;
hsa-mir-3140-3p
;
hsa-mir-3116
;
hsa-mir-1254
;
hsa-mir-4790-3p
;
hsa-mir-6730-3p
;
hsa-mir-4680-3p
;
hsa-mir-5187-3p
;
hsa-mir-4427
;
hsa-mir-4653-5p
;
hsa-mir-3921
;
hsa-mir-301b-5p
;
hsa-mir-301a-5p
;
hsa-mir-4315
;
hsa-mir-146a-3p
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-6891-3p
;
hsa-mir-6072
;
hsa-mir-6754-5p
;
hsa-mir-4441
;
hsa-mir-4270
;
hsa-mir-211-3p
;
hsa-mir-4748
;
hsa-mir-329-5p
;
hsa-mir-4464
;
hsa-mir-7845-5p
;
hsa-mir-888-3p
;
hsa-mir-4506
;
hsa-mir-26b-5p
;
hsa-mir-34a-5p
;
hsa-mir-155-3p
;
hsa-mir-130b-3p
;
hsa-mir-1296-5p
;
hsa-mir-133a-3p
;
hsa-mir-3622b-5p
;
hsa-mir-22-3p
Nearest TSS
ENST00000595228/Upstream/5863;
ENST00000584053/Downstream/16;
Nearest CpG islands
chr17-CpG: 56/Target
, None/Upstream, None/Downstream
Nearby gene
MIEN1
;
IKZF3
(+) ;
Nearest cancer related gene
MIEN1
(OG, No orient, 0)
Upstream sequence
TGGGAGCCTCACACTGGCAAGCCTGGACCTCTGCTCACACCCGCAAACCAACTGAATCTCTCACTCCTCCGTGCCTCAGCCACCTCCCACGGGCACCTGC
Downstream sequence
TAAGACAGACGTCTCTGCGGGCTGCGGGGAGATGTGGGGAGGGCCCCCTCCACTTTGGAGGGCAGTGAAGGAGAGGGATCCTCTAAATTGTCGAGGCTTC
Target sequence
TGGTCTAATTAGTGCTAAGGGAATCAGGGTGTAGGACTGATCTGTCTTTTTCAGAAACTAAGAAATTTTAAAAGTGTATCACAGAAAGAAATGAAGCATA
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Sample Information
×
Sample name
SGCX-NOR-076
Sample type
Tumor
Age
43
Gender
Female
CpG Island Information
×
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