Basic Information
VIS ID
TVIS20005102
Fusion event
HPV-chr17:q12 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
End
37895008/39738755 (Hg38)
Location type
Intronic
Target gene
Nearest CpG islands
chr17-CpG: 56/Target, None/Upstream, None/Downstream
Nearby gene
MIEN1 ; IKZF3(+) ;
Nearest cancer related gene
MIEN1(OG, No orient, 0)
Upstream sequence
TGGGAGCCTCACACTGGCAAGCCTGGACCTCTGCTCACACCCGCAAACCAACTGAATCTCTCACTCCTCCGTGCCTCAGCCACCTCCCACGGGCACCTGC
Downstream sequence
TAAGACAGACGTCTCTGCGGGCTGCGGGGAGATGTGGGGAGGGCCCCCTCCACTTTGGAGGGCAGTGAAGGAGAGGGATCCTCTAAATTGTCGAGGCTTC
Target sequence
TGGTCTAATTAGTGCTAAGGGAATCAGGGTGTAGGACTGATCTGTCTTTTTCAGAAACTAAGAAATTTTAAAAGTGTATCACAGAAAGAAATGAAGCATA
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
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