Basic Information
VIS ID
TVIS20005103
Fusion event
HPV-chr2:q22.3 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV31
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
146327290/145569722 (Hg38)
End
146342732/145585164 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2K
Nearest miRNA
hsa-mir-128-1/Upstream/4983037; hsa-mir-10b/Downstream/3745114;
Nearest TSS
ENST00000437798/Upstream/237875; ENST00000414967/Downstream/2860;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1045234, chr2-CpG: 49/Downstream/1002069
Nearby gene
TEX41 ; PABPC1P2(+) ;
Upstream sequence
ttcctattcagacggggcctgcctgagattctgatttatataaataataataaataatgtggatgctgctgattcagggaccatactacaagtagcaGTA
Downstream sequence
gtacacacaTTCCTAGCCTGGTCAATTTAGATCTGATAATATTCTTTTTCCTCTTATGGACAAGGATAGTTATATATGAAATCCAAAGTGGGCCTGGAGT
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate