VISDB Viral Integration Site DataBase

VIS ID

TVIS20005107

Fusion event

HPV-TP63 integration

Validated

Yes

Detection method

RNA-Seq+RT-PCR

Data source

Curated

Sample type

Disease

Squamous-cell carcinoma (SCC)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HPV

Subtype

HPV56

Reference genome

Not given

Chromosome

chr3

Cytoband

q28

Reference genome

Start

End

189607242/189889453 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-203a-3p ; hsa-mir-92a-3p ; hsa-mir-21-5p ; hsa-mir-124-3p ; hsa-mir-301b-3p ; hsa-mir-129-5p ; hsa-mir-6885-3p ; hsa-mir-4477b ; hsa-mir-1178-3p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428

Nearest miRNA

hsa-let-7g/Upstream/50062; hsa-mir-3137/Downstream/5245053;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/932308, chr3-CpG: 99/Downstream/230838

Nearby gene

TPRG1 ; P3H2(+) ;

Nearest cancer related gene

TP63(TSG, No orient, 0)

Upstream sequence

aagttccaaattgtatctctcgtagtcaattggtaatagagaactcctcatgaggccataggtgcaggctgggagagataatgtaatttaccaggagcag

Downstream sequence

CTCCGTATCCCACAGATTGCAGCATTGTCAGGTGAGTCCACAGCATGTGCCCCTGGGGGCCTGCCCTAAGCATCCCGGGATGGTGGAGGGCGGATACTGT

Target sequence

ATGATTCACTTTGTTATGTGGTTATTCAAATGGATGTCTGCTGTCTTCAGAGGCTTTAAACTTTCTCTGGGAAGAGATCTTGTTTTATTATTCATTCTTTCATTAATTTATTCATGCAGGAAATGTTTATTGTACAATGGTGGTTCAGGCCTGCTTTCAAGGATCTTATTATCTAAGTACAAGAAAAGAAAACATAAACCAGTTTTTAAAGAGCATGTTA