VISDB Viral Integration Site DataBase

VIS ID

TVIS20005108

Fusion event

HPV-BCL2L13 integration

Validated

Yes

Detection method

RNA-Seq+RT-PCR

Data source

Curated

Sample type

Disease

Squamous-cell carcinoma (SCC)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HPV

Subtype

HPV33

Reference genome

Not given

Chromosome

chr22

Cytoband

q11.21

Reference genome

Start

End

18116389/17633623 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-34a-5p ; hsa-mir-10a-5p ; hsa-mir-192-5p ; hsa-mir-1301-3p ; hsa-mir-125b-5p ; hsa-mir-580-3p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-539-5p ; hsa-mir-6783-5p ; hsa-mir-6891-5p ; hsa-mir-4779 ; hsa-mir-3173-3p ; hsa-mir-100-3p ; hsa-mir-6808-5p ; hsa-mir-6833-5p ; hsa-mir-6079 ; hsa-mir-3190-3p ; hsa-mir-3689f ; hsa-mir-3689e ; hsa-mir-3689b-5p ; hsa-mir-3689a-5p ; hsa-mir-6799-5p ; hsa-mir-548au-3p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-671-5p ; hsa-mir-6828-5p ; hsa-mir-190b ; hsa-mir-190a-5p ; hsa-mir-6134 ; hsa-mir-4530 ; hsa-mir-6754-5p ; hsa-mir-4270 ; hsa-mir-4441 ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-6865-5p ; hsa-mir-6815-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6510-5p ; hsa-mir-34c-5p ; hsa-mir-449a ; hsa-mir-449b-5p ; hsa-mir-6878-3p ; hsa-mir-629-3p ; hsa-mir-4290 ; hsa-mir-7112-5p ; hsa-mir-877-3p ; hsa-mir-6872-3p

Nearest miRNA

hsa-let-7a-3/Downstream/130557;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/4151, chr22-CpG: 69/Downstream/4891

Nearby gene

ATP6V1E1 ; BID(+) ;

Upstream sequence

tggccaggttggtctcgaactcctggcctcaggtgatccacccgcctcagcctcccagagtgctaggattacaggcatgagccactgcgcctgaccACGA

Downstream sequence

AACTCTGGAGTTTGCTCAGGAGGACAAAGCGCGAAAGACTAGAAGTAAATGTAAATCATCTGTCTTTAAATGTTGAGCAAATAATTTGAAAAGGAAAAAA

Target sequence

TTTACTTATTTTTATTTTGAGACATTAGAAAATACAAAAAAGTACAAAGAATAATTTATTCCCATACCATGCACCACTACCCAAAATTAACAATTAACATTTGTCACATTTACTTCAAGACTTCACTTGAAAAACAAATCGTAGGTATAGTTACTATCCCCTTTTGCAGCACCCACTTCTCCCCCATGTTAGTTTCTCTTTAAAACTCAATTTTCTTCAGTTTTGCTGATTCACCAAGGAACAGGCCAGGTCCTG