Basic Information
VIS ID
TVIS20005110
Fusion event
HPV-chr2:q22.3 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
HQ644271.1
Host Sequence
Chromosome
chr2
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
146433284/145675716 (Hg38)
End
146455354/145697786 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2K
Nearest miRNA
hsa-mir-128-1/Upstream/5089031; hsa-mir-10b/Downstream/3632492;
Nearest TSS
ENST00000437798/Upstream/72293; ENST00000414967/Downstream/217304;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1151228, chr2-CpG: 49/Downstream/889447
Nearby gene
TEX41 ; PABPC1P2(+) ;
Upstream sequence
actccactacgcccatctccgccactccggattcggggatctgaacccgactccctttcgatccgctgagggcaagggaggccattgcctgtcccttcgg
Downstream sequence
atgttctcactcataggtgggaactgaacaatgagaacacagggacacaggaaggggaacatcacacactggggcctgtcgtggggtgggggaatggggg
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate