VISDB Viral Integration Site DataBase

VIS ID

TVIS20005114

Fusion event

HPV-AGO2 integration

Validated

Yes

Detection method

RNA-Seq+RT-PCR

Data source

Curated

Sample type

Disease

Adenosquamous carcinoma (ASC)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HPV

Subtype

HPV16

Reference genome

Chromosome

chr8

Cytoband

q24.3

Reference genome

Start

End

141603490/140593391 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-376a-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-107 ; hsa-mir-99a-5p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-671-5p ; hsa-mir-652-3p ; hsa-mir-186-5p ; hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-3120-3p ; hsa-mir-3133 ; hsa-mir-184 ; hsa-mir-4795-3p ; hsa-mir-223-5p ; hsa-mir-5193 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-5002-5p ; hsa-mir-125a-3p ; hsa-mir-126-5p ; hsa-mir-548l ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548w ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548bb-5p ; hsa-mir-548c-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-6887-5p ; hsa-mir-548a-5p ; hsa-mir-6795-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-8085 ; hsa-mir-4723-5p ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6133 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4524a-3p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-6751-5p ; hsa-mir-6803-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-6811-5p ; hsa-mir-1275 ; hsa-mir-6511b-5p ; hsa-mir-6793-5p ; hsa-mir-92a-1-5p ; hsa-mir-6769b-5p ; hsa-mir-92a-2-5p ; hsa-mir-6769a-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-6878-5p ; hsa-mir-625-5p ; hsa-mir-1193 ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-6841-3p ; hsa-mir-873-5p ; hsa-mir-6895-5p ; hsa-mir-583 ; hsa-mir-6825-5p ; hsa-mir-3144-5p ; hsa-mir-6781-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-3649 ; hsa-mir-6797-5p ; hsa-mir-6077 ; hsa-mir-1249-5p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-3918 ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-6165 ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-3175 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-8055 ; hsa-mir-8081 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-4785 ; hsa-mir-6755-3p ; hsa-mir-3613-3p ; hsa-mir-5094 ; hsa-mir-944 ; hsa-mir-548c-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-148a-3p ; hsa-mir-374b-3p ; hsa-mir-4766-3p ; hsa-mir-6792-5p ; hsa-mir-4522 ; hsa-mir-646 ; hsa-mir-548p ; hsa-mir-3664-5p ; hsa-mir-590-5p ; hsa-mir-4799-5p ; hsa-mir-506-5p ; hsa-mir-6074 ; hsa-mir-892c-5p ; hsa-mir-103a-3p ; hsa-mir-491-3p ; hsa-mir-4509 ; hsa-mir-4699-3p ; hsa-mir-3680-3p ; hsa-mir-302c-5p ; hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-802 ; hsa-mir-3908 ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-3121-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-4744 ; hsa-mir-548e-5p ; hsa-mir-4666a-5p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-95-5p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-4495 ; hsa-mir-5582-5p ; hsa-mir-4719 ; hsa-mir-4803 ; hsa-mir-5692a ; hsa-mir-548an ; hsa-mir-382-3p ; hsa-mir-124-3p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-6827-5p ; hsa-mir-505-5p ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-6852-5p ; hsa-mir-6742-3p ; hsa-mir-939-3p ; hsa-mir-8064 ; hsa-mir-1911-5p ; hsa-mir-4682 ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-6777-3p ; hsa-mir-4714-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-513b-5p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-145-3p ; hsa-mir-466 ; hsa-mir-4643 ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-31-3p ; hsa-mir-6832-3p ; hsa-mir-4328 ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-578 ; hsa-mir-132-3p ; hsa-mir-1207-5p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-1298-3p ; hsa-mir-204-3p ; hsa-mir-3192-5p ; hsa-mir-3197 ; hsa-mir-3616-3p ; hsa-mir-3691-3p ; hsa-mir-3910 ; hsa-mir-4270 ; hsa-mir-4314 ; hsa-mir-4441 ; hsa-mir-4646-5p ; hsa-mir-4668-3p ; hsa-mir-4763-3p ; hsa-mir-510-3p ; hsa-mir-5187-5p ; hsa-mir-542-5p ; hsa-mir-602 ; hsa-mir-605-3p ; hsa-mir-6087 ; hsa-mir-6125 ; hsa-mir-619-5p ; hsa-mir-6506-5p ; hsa-mir-658 ; hsa-mir-6754-5p ; hsa-mir-6765-5p ; hsa-mir-6804-5p ; hsa-mir-6820-5p ; hsa-mir-8063 ; hsa-mir-92b-5p ; hsa-mir-10b-3p ; hsa-mir-181b-2-3p ; hsa-mir-181b-3p ; hsa-mir-2115-5p ; hsa-mir-2277-3p ; hsa-mir-34c-3p ; hsa-mir-3619-3p ; hsa-mir-3620-3p ; hsa-mir-3660 ; hsa-mir-3690 ; hsa-mir-4256 ; hsa-mir-4308 ; hsa-mir-4420 ; hsa-mir-4526 ; hsa-mir-4690-3p ; hsa-mir-4755-5p ; hsa-mir-4776-5p ; hsa-mir-5006-3p ; hsa-mir-504-5p ; hsa-mir-516a-3p ; hsa-mir-516b-3p ; hsa-mir-520a-3p ; hsa-mir-5685 ; hsa-mir-623 ; hsa-mir-6719-3p ; hsa-mir-6730-3p ; hsa-mir-6856-3p ; hsa-mir-7162-5p

Nearest miRNA

hsa-mir-1204/Upstream/5736176; hsa-mir-10400/Downstream/139173;

Nearest TSS

Nearest CpG islands

chr8-CpG: 20/Target, None/Upstream, None/Downstream

Nearby gene

CHRAC1 ; PTK2(+) ;

Upstream sequence

acaaatgtgtgttattttatgcatctgagtttgaaacaattcattccagcagccatgggaaatgaatccaCCTGCCCTGCTCTGGAGGCAGCCAGCAGCT

Downstream sequence

atgttggccaggctggtctcaaactcctgacctcaggtgatccacccgcctcggcctcccaaagtgctgggattacaggtgtgagccactgtgcccggcc