Basic Information
VIS ID
TVIS20005115
Fusion event
HPV-chr2:q22.3 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Tumor
Disease
Adenocarcinoma (AC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
146400095/145642527 (Hg38)
End
146485051/145727483 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2K
Nearest miRNA
hsa-mir-128-1/Upstream/5055842; hsa-mir-10b/Downstream/3602795;
Nearest TSS
ENST00000437798/Upstream/39104; ENST00000414967/Downstream/187607;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1118039, chr2-CpG: 49/Downstream/859750
Nearby gene
TEX41 ; PABPC1P2(+) ;
Upstream sequence
GATGTGTGAAGGGCCTGGCCAAGCTCTCTGCATATCTCAAGTCCCCAGGCCTTGTGGGTCCCTTGTCCTCCTTGGATACATGGCACCTGCTCTTTCTGGC
Downstream sequence
gcactccccacttcctgaacccctattcaccaaattatctttaaaaactccaatccctgaatgcttggggagactgatttgagtaataataaatctccgg
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate