Basic Information
VIS ID
TVIS20005118
Fusion event
HPV-GATA5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Good
Reported year
2014
PubMed ID
24390348
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
HQ644271.1
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
61031494/62456438 (Hg38)
End
61070167/62495111 (Hg38)
Location type
Intronic
Target gene
GATA5
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/123881; hsa-mir-1-1/Downstream/59195;
Nearest TSS
ENST00000382410/Upstream/25665; ENST00000624914/Downstream/20985;
Nearest CpG islands
chr20-CpG: 41/Target, None/Upstream, None/Downstream
Nearest cancer related gene
GATA5(TSG, No orient, 0)
Upstream sequence
atcctgggtcagccacttaatagttatgcgaccttgacaagttgcataacctctctgtgcctcagttcccttatatagaacatgggggtaatgctagcac
Downstream sequence
GCGCTGGCCTTGGGTGCAGATCGAGCGCCAGGATGGGGCCTGACACTCAATTCTTCTCCTTTGAGGCTCAGGGAGATGTCAGTTGGCTTGAAAAACCGCC
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate