Basic Information
VIS ID
TVIS20005122
Fusion event
HPV-chr4:q22.2 integration
Validated
Yes
Detection method
RNA-Seq+RT-PCR
Data source
Curated
Sample type
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr4
Cytoband
q22.2
Reference genome
End
94789178/93868027 (Hg38)
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-12113/Upstream/6567088; hsa-mir-1243/Downstream/5129360;
Nearby gene
ATOH1 ; SMARCAD1(+) ;
Upstream sequence
gctagagaggaagttattgtttaatgacaagagtttcaagttttgcaaaatgaaaagagttctgtggatagatggtggtgatgaagcacacaatgtgaat
Downstream sequence
gatcacacactgacttcttgttattcttatgatcccatctcccctcaattcctgccacactaattccttgcccttctttggacatcctgaacgtactcct
Target sequence
aaccttttcagttgttcagattaaaaatctcgcagtcatcgatgactcctctttttcttttacaggcaatccatcaaacaaatcctgtttgctcacctttcaaaatatgtctggaatacaacccctgctactcgactggttccaccctgttgtatgccaccatcacttcttgcctgaaatatagtaataacctctccccggcttttcccaggcttcccatatcctattctcaacacagtagcagagtgtttcttc
Reference
Ojesina, A. I., et al. Landscape of genomic alterations in cervical carcinomas. Nature,2014,506(7488): 371-375.
Curate