Basic Information
VIS ID
TVIS30000002
Fusion event
HIV-ABCA11P integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
442619/448830 (Hg38)
End
442619/448830 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
ABCA11P
Nearest miRNA
hsa-mir-571/Upstream/98578; hsa-mir-12113/Downstream/1537554;
Nearest TSS
ENST00000502981/Upstream/32293; ENST00000514953/Downstream/25221;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/62220, chr4-CpG: 33/Downstream/24852
Upstream sequence
tataaagctgaacagctagattaataaaatctgccaaaaatacaaactcacacacggtcacatgaagagttttagacactcataattactgcagcattgt
Downstream sequence
tactgaaagcaaataaatgcaacacagatttctctcaccaaattgataaatttgaaatattaaaatgaaatattactcagtttgtaaaaagcaaaaatta
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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