Basic Information
VIS ID
TVIS30000028
Fusion event
HIV-chr22 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr22
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
25859914/25463947 (Hg38)
End
25859914/25463947 (Hg38)
Orient
-
Location type
Inergenic
Nearest miRNA
hsa-mir-1286/Upstream/8236; hsa-let-7a-3/Downstream/1091265;
Nearest TSS
ENST00000624155/Upstream/26124; ENST00000455558/Downstream/100203;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/42375, chr22-CpG: 108/Downstream/100694
Nearby gene
CRYBB2P1(+2269) ;
Upstream sequence
aaataacctacatgtccatgagaaggggaatgagtaaataatcagcatgcaataatatcatcatgccacagacaaaagggatacacaacaccttacatat
Downstream sequence
tcaacatgggcatatctcagaaacattcccggaggtaaaacaaaacaaacaaaaaaaacaggcaagttacagaacaatgtttgatatttataAGAATttt
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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