Basic Information
VIS ID
TVIS30000029
Fusion event
HIV-chr10 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
6633011/6591049 (Hg38)
End
6633011/6591049 (Hg38)
Orient
+
Location type
Inergenic
Nearest miRNA
hsa-mir-3155a/Upstream/438772; hsa-mir-107/Downstream/5539711;
Nearest TSS
ENST00000439456/Upstream/10748; ENST00000448835/Downstream/27667;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/10369, chr10-CpG: 30/Downstream/580831
Nearby gene
PRKCQ-AS1(+5688) ;
Upstream sequence
GAGTTGAAAATCTTCCTAAACTGCTGGAGGATACACCTCTGATAGCTTGAGACAAATATCCTCTTGATCATTGTTTCACCATATTTGTCTTTGCTCATGG
Downstream sequence
AGAACCATTTTGATCCGTGGTTTAGCCTCCCAGGTGATTGAACAATACCGGTGATCTGAGGCAGACCCTCTGTGACGGATAACAGGTGAGTCTCTTGCAT
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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