Basic Information
VIS ID
TVIS30000036
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
198543475/198574345 (Hg38)
End
198543475/198574345 (Hg38)
Orient
+
Location type
Inergenic
Fragile sites / regions
FRA1K
Nearest miRNA
hsa-mir-101-1/Upstream/1991864; hsa-mir-1182/Downstream/284528;
Nearest TSS
ENST00000473358/Upstream/33400; ENST00000367364/Downstream/24523;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/415111, chr1-CpG: 36/Downstream/1461001
Nearby gene
ATP6V1G3(-33400) ;
Upstream sequence
TTTGCCTTCTAGAGCCTCATGGATTTAAAAAGACAAGACCAGGAAAAATATAGAGGATTTCCTTCTGCCCCTTGTTTGGAAAGCATGGCTTTTTCAAGGA
Downstream sequence
GATTAAAACTAATTTTTATTCAGGCTGTAAATATAATATATAATTATCCAAACAGAAGAGATCTTCACTGATAAAAAAATACCCCAAATTCAGCATATTT
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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