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TVIS30000039
Basic Information
VIS ID
TVIS30000039
Fusion event
HIV-TRAPPC10 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
45462384/44042503 (Hg38)
End
45462384/44042503 (Hg38)
Orient
-
Location type
Intronic
Target gene
TRAPPC10
miRNAs that regulate target gene
hsa-mir-186-5p
;
hsa-mir-330-5p
;
hsa-mir-615-3p
;
hsa-mir-18a-3p
;
hsa-mir-193b-3p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-4713-5p
;
hsa-mir-2116-3p
;
hsa-mir-532-3p
;
hsa-mir-150-5p
;
hsa-mir-4762-5p
;
hsa-mir-4753-3p
;
hsa-mir-130b-5p
;
hsa-let-7a-5p
;
hsa-let-7b-5p
;
hsa-let-7c-5p
;
hsa-let-7d-5p
;
hsa-let-7e-5p
;
hsa-let-7f-5p
;
hsa-let-7g-5p
;
hsa-let-7i-5p
;
hsa-mir-1233-5p
;
hsa-mir-1249-5p
;
hsa-mir-1294
;
hsa-mir-1321
;
hsa-mir-149-3p
;
hsa-mir-202-3p
;
hsa-mir-3921
;
hsa-mir-4278
;
hsa-mir-4316
;
hsa-mir-4419a
;
hsa-mir-4458
;
hsa-mir-4468
;
hsa-mir-4500
;
hsa-mir-4510
;
hsa-mir-4653-5p
;
hsa-mir-4682
;
hsa-mir-4685-5p
;
hsa-mir-4716-3p
;
hsa-mir-4723-5p
;
hsa-mir-4728-5p
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-503-5p
;
hsa-mir-5088-5p
;
hsa-mir-5698
;
hsa-mir-6127
;
hsa-mir-6129
;
hsa-mir-6130
;
hsa-mir-6133
;
hsa-mir-6732-5p
;
hsa-mir-6785-5p
;
hsa-mir-6794-5p
;
hsa-mir-6797-5p
;
hsa-mir-6805-5p
;
hsa-mir-6825-5p
;
hsa-mir-6837-5p
;
hsa-mir-6870-5p
;
hsa-mir-6883-5p
;
hsa-mir-7111-5p
;
hsa-mir-760
;
hsa-mir-98-5p
Nearest miRNA
hsa-let-7c/Upstream/432514; hsa-mir-6815/Downstream/1435763;
Nearest TSS
ENST00000624081/Upstream/30178;
ENST00000481460/Downstream/36973;
Nearest CpG islands
None/Target,
chr21-CpG: 261/Upstream/29406
,
chr21-CpG: 103/Downstream/64572
Upstream sequence
agctttttagcttacagaaaaaaaaagattaaaaaaattttgtttagaaatttctagctttattgcattgtgttcagaaagtgtttatatttttgcttta
Downstream sequence
tgaaacttatttttaaaattttatgaatttgactgttgtgtgacctaataaatgatcagtttttttggacatttcatgtgtgtttgagaatgtattttct
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
Sample Information
×
Sample name
Patient1
Sample type
PBMC
Age
59
Gender
Male
CpG Island Information
×
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