Basic Information
VIS ID
TVIS30000041
Fusion event
HIV-chr7 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
12278617/12238991 (Hg38)
End
12278617/12238991 (Hg38)
Orient
-
Location type
Inergenic
Nearest miRNA
hsa-mir-339/Upstream/5171946; hsa-mir-10399/Downstream/5888229;
Nearest TSS
ENST00000635602/Upstream/8633; ENST00000443874/Downstream/94735;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/27403, chr7-CpG: 45/Downstream/164546
Nearby gene
TMEM106B(+1727) ;
Upstream sequence
aggattttcaggatggcaaatgagcattggcttcaacttaaagtcaccagctacattcaccactaaagagagtcagcctgtcctttaaagctttaaaggc
Downstream sequence
aagcattgacttctctttagctatgaaagttttagatggcacctttttgtaaaagaaggttgttttatctacattgaaaatatattgttcattgtaacca
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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