Basic Information
VIS ID
TVIS30000055
Fusion event
HIV-EP400P1 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
GRCh37/hg19
Start
132591574/132107029 (Hg38)
End
132591574/132107029 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA12E
Target gene
EP400P1
Nearest miRNA
hsa-let-7i/Upstream/3812851; hsa-mir-6763/Downstream/474968;
Nearest TSS
ENST00000382841/Upstream/23250; ENST00000541954/Downstream/32944;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/21859, chr12-CpG: 58/Downstream/9652
Upstream sequence
TAAGCAGTGTAACAGCTTCCATAGTCACATGAAGAGTAAGTTCATCGTTGTATTAAAGTTTACTTCTAAATGATAGAAATAAGTTTTTATAGAACCTGAC
Downstream sequence
TAGCGTCTTCGGAATCTATGTTTTATCATCATTTTATAGGAAAATACCGGAAGTTGACTAACATTTGGGTTTTTCGTGAATATTTTCCTCTGTGTAATAT
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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