Basic Information
VIS ID
TVIS30000056
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
178508622/178539487 (Hg38)
End
178508622/178539487 (Hg38)
Orient
+
Location type
Inergenic
Nearest miRNA
hsa-mir-101-1/Upstream/1510042; hsa-mir-1182/Downstream/138262;
Nearest TSS
ENST00000473358/Upstream/18658; ENST00000367638/Downstream/3265;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/52336, chr1-CpG: 83/Downstream/2740
Nearby gene
C1orf220(+3309) ;
Upstream sequence
CAAGGCGGCTGGCAGCAGGAGATGCAGGCGAGGCCAAGCTGTGGCCAGGCTGTGGTGAGGATACCGTGGCCGGGACTGCTGCCACAGGACACAGGATGCT
Downstream sequence
ACTCTCACAGATGGTCTCCTGGCCTAGCTGCCATGGCCAAAAATAAGTTCTCTTCTGTTCCTGCACCCTAGCCTTCAAAGCCCCACTGGGCTGGGCAGGA
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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