Basic Information
VIS ID
TVIS30000057
Fusion event
HIV-RELA-DT integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
65437942/65670471 (Hg38)
End
65437942/65670471 (Hg38)
Orient
-
Location type
Inergenic
Fragile sites / regions
FRA11H
Target gene
RELA-DT
Nearest miRNA
hsa-mir-10392/Upstream/21218; hsa-let-7a-2/Downstream/1263963;
Nearest TSS
ENST00000527297/Upstream/7377; ENST00000532042/Downstream/41525;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/6863, chr11-CpG: 59/Downstream/41407
Nearby gene
RELA(-7499) ;
Upstream sequence
atttatgttgtataatattcatgacattgaatttggcagtgatttcttggatacaacataaaagcacagaccacaaaagaaaaaaataaattaggcttat
Downstream sequence
aaaaattaaaaacttttgtacatcaaatacaatatactgaagtaaaaaatcaacccacagaatggtaggaaatatttcaaattacatatctgataaggat
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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