Basic Information
VIS ID
TVIS30000058
Fusion event
HIV-chr21 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
34575338/33203033 (Hg38)
End
34575338/33203033 (Hg38)
Orient
+
Location type
Inergenic
Nearest miRNA
hsa-let-7c/Upstream/2827655; hsa-mir-3197/Downstream/347629;
Nearest TSS
ENST00000624081/Upstream/32384; ENST00000420068/Downstream/26868;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/130796, chr21-CpG: 94/Downstream/26903
Nearby gene
IFNAR2(+26862) ;
Upstream sequence
TGGAGGGTCACCTAACCCACACTGGGGTGTGAGATCGCATCACCAACCCCAACAGACTCGGGGCTGTGTTGGGGTGGGGGGTGCCGAAGTTCTAGCCTCG
Downstream sequence
GGGTCAAGCCACTTCTGATCACAATCCAATTCACCCACATCACACACACCATGGcacacacatcatacacacacatacacaccatgcaaacatcacatac
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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