Basic Information
VIS ID
TVIS30000062
Fusion event
HIV-S100PBP integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p35.1
Reference genome
GRCh37/hg19
Start
33299303/32833702 (Hg38)
End
33299303/32833702 (Hg38)
Orient
-
Location type
Intronic
Target gene
S100PBP
miRNAs that regulate target gene
hsa-let-7a-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-944
Nearest miRNA
hsa-mir-12136/Upstream/746695; hsa-mir-101-1/Downstream/498691;
Nearest TSS
ENST00000473358/Upstream/8805; ENST00000525203/Downstream/13100;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/15397, chr1-CpG: 74/Downstream/36963
Upstream sequence
ccgcccaccttggcctcccaaagtgctgggattacaggcgtgagacagcacccagcccattttttattctttcagacattagaaataatgattctctctc
Downstream sequence
ctacaaagaaaaaaacttaaaatcacctataaatctatcctgccacctagaaataacaaaattaacattttgataattatctttcctgtAAGGTAGAATA
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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