Basic Information
VIS ID
TVIS30000064
Fusion event
HIV-chr14 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr14
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
35178258/34709052 (Hg38)
End
35178258/34709052 (Hg38)
Orient
+
Location type
Inergenic
Nearest miRNA
hsa-mir-208a/Upstream/3694310; hsa-mir-1185-1/Downstream/2243257;
Nearest TSS
ENST00000550708/Upstream/78869; ENST00000557373/Downstream/4776;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/78780, chr14-CpG: 76/Downstream/5127
Nearby gene
CFL2(-1330) ;
Upstream sequence
tatgattgtgccactgcacagcagcctgggcaatagagtgaaaccctgtccaaaaaagaagaaaaaaaTGTGTGTGtatgtgtgtatatatacatatata
Downstream sequence
tatacatatatatatgtaCACACACGGAAGTTACAAAAATAGAGGTTCAATGATCTGTAATACATCTTTTAACAAAAACATTTAATATTTATCTACTTAC
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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