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TVIS30000066
Basic Information
VIS ID
TVIS30000066
Fusion event
HIV-RPS6KA5 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr14
Cytoband
q32.11
Reference genome
GRCh37/hg19
Start
91393518/90927174 (Hg38)
End
91393518/90927174 (Hg38)
Orient
-
Location type
Intronic
Target gene
RPS6KA5
miRNAs that regulate target gene
hsa-mir-148a-3p
;
hsa-mir-128-3p
;
hsa-mir-101-3p
;
hsa-mir-27a-3p
;
hsa-mir-744-5p
;
hsa-mir-93-5p
;
hsa-mir-19a-3p
;
hsa-mir-4437
;
hsa-mir-24-3p
;
hsa-mir-4635
;
hsa-mir-5088-5p
;
hsa-mir-548n
;
hsa-mir-1-5p
;
hsa-mir-340-5p
;
hsa-mir-142-5p
;
hsa-mir-5590-3p
;
hsa-mir-526b-3p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-195-3p
;
hsa-mir-16-2-3p
;
hsa-mir-664a-3p
;
hsa-mir-6504-3p
;
hsa-mir-5586-3p
;
hsa-mir-376c-3p
;
hsa-mir-301b-3p
;
hsa-mir-454-3p
;
hsa-mir-301a-3p
;
hsa-mir-3666
;
hsa-mir-130a-3p
;
hsa-mir-130b-3p
;
hsa-mir-4295
;
hsa-mir-106a-3p
;
hsa-mir-6834-5p
;
hsa-mir-8077
;
hsa-mir-4663
;
hsa-mir-7160-5p
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-6875-5p
;
hsa-mir-3126-5p
;
hsa-mir-4728-3p
;
hsa-mir-4735-3p
;
hsa-mir-18b-5p
;
hsa-mir-18a-5p
;
hsa-mir-548m
;
hsa-mir-539-3p
;
hsa-mir-485-3p
;
hsa-mir-5003-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-4796-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-335-3p
;
hsa-mir-5096
;
hsa-mir-6083
;
hsa-mir-4446-5p
;
hsa-mir-4282
;
hsa-mir-526b-5p
;
hsa-mir-5698
;
hsa-mir-744-3p
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-143-5p
;
hsa-mir-3650
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-6499-3p
;
hsa-mir-367-5p
;
hsa-mir-1267
;
hsa-mir-129-5p
;
hsa-mir-135a-3p
;
hsa-mir-153-3p
;
hsa-mir-3680-3p
;
hsa-mir-448
;
hsa-mir-450b-5p
;
hsa-mir-507
;
hsa-mir-557
;
hsa-mir-5584-5p
;
hsa-mir-6750-5p
;
hsa-mir-6822-5p
;
hsa-mir-9500
Nearest miRNA
hsa-mir-1260a/Upstream/13660884; hsa-mir-1185-1/Downstream/3021052;
Nearest TSS
ENST00000550708/Upstream/15705;
ENST00000521081/Downstream/51350;
Nearest CpG islands
None/Target,
chr14-CpG: 35/Upstream/110570
,
chr14-CpG: 134/Downstream/132715
Upstream sequence
tggtcatgatcgtttgagagataatggataatttcagactctgttaagtcagagcacaagtctaaaatcagggtaatattacagaaatgccttgtgtata
Downstream sequence
aaaatagataagtaaataaaatcagggtaataactactaaaagaacagaaatagaatatacatgacttccagaccattaggcggacatgaaatcaaaaga
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
Sample Information
×
Sample name
Patient2
Sample type
PBMC
Age
55
Gender
Male
CpG Island Information
×
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