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TVIS30000072
Basic Information
VIS ID
TVIS30000072
Fusion event
HIV-TNRC6C integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
76065696/78069615 (Hg38)
End
76065696/78069615 (Hg38)
Orient
-
Location type
Intronic
Target gene
TNRC6C
miRNAs that regulate target gene
hsa-mir-30b-5p
;
hsa-mir-4509
;
hsa-mir-4643
;
hsa-mir-95-5p
;
hsa-mir-320a
;
hsa-mir-331-5p
;
hsa-mir-320b
;
hsa-mir-320c
;
hsa-mir-548m
;
hsa-mir-320d
;
hsa-mir-4429
;
hsa-mir-4666a-5p
;
hsa-mir-125b-2-3p
;
hsa-mir-380-3p
;
hsa-mir-378a-5p
;
hsa-mir-1200
;
hsa-mir-4666b
;
hsa-mir-212-3p
;
hsa-mir-132-3p
;
hsa-mir-4709-5p
;
hsa-mir-7159-5p
;
hsa-mir-1273e
;
hsa-mir-580-3p
;
hsa-mir-539-5p
;
hsa-mir-4635
;
hsa-mir-1264
;
hsa-mir-7152-5p
;
hsa-mir-3074-5p
;
hsa-mir-5700
;
hsa-mir-6512-5p
;
hsa-mir-548ay-3p
;
hsa-mir-548at-3p
;
hsa-mir-548as-3p
;
hsa-mir-548t-3p
;
hsa-mir-548ap-3p
;
hsa-mir-548aa
;
hsa-mir-629-3p
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-3925-3p
;
hsa-mir-766-3p
;
hsa-mir-1305
;
hsa-mir-4652-3p
;
hsa-mir-421
;
hsa-mir-505-3p
;
hsa-mir-8064
;
hsa-mir-3182
;
hsa-mir-216b-3p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-5010-3p
;
hsa-mir-1238-3p
;
hsa-mir-670-3p
;
hsa-mir-6844
;
hsa-mir-6881-3p
;
hsa-mir-6780a-3p
;
hsa-mir-7111-3p
;
hsa-mir-877-3p
;
hsa-mir-4677-5p
;
hsa-mir-22-5p
;
hsa-mir-2116-5p
;
hsa-mir-676-5p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-511-5p
;
hsa-mir-502-5p
;
hsa-mir-6830-3p
;
hsa-mir-1915-5p
;
hsa-mir-6841-3p
Nearest miRNA
hsa-mir-10226/Upstream/672561; hsa-mir-1250/Downstream/1637561;
Nearest TSS
ENST00000595228/Upstream/4721;
ENST00000592251/Downstream/21752;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/28373
,
chr17-CpG: 33/Downstream/34983
Upstream sequence
tgggtctacaggtgcatgccactctgcccaactaattttattttttattttttctgtagagacagagtctcactttgtggcATTTATACAgttttgtatt
Downstream sequence
gcagcatttttgtagtaaaaagataacaataatttatgtgtacattgatggagtaacaagttaattatgtcacttctacattatacagaactaaaaggaa
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
Sample Information
×
Sample name
Patient2
Sample type
PBMC
Age
55
Gender
Male
CpG Island Information
×
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