Basic Information
VIS ID
TVIS30000075
Fusion event
HIV-MTMR3 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
End
30289343/29893354 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1286/Upstream/1433406; hsa-let-7a-3/Downstream/113695;
Upstream sequence
TCAACCTTTCACATATCCCTTTACTTTCTCTTAAGATACTTTCATGGTGACAAAAAAAATACTCTTAATGTCATTCCTTTCACTGTGTGTGTAACTCCTG
Downstream sequence
TGGCAAGACTGTATATTTGTATGTATGTATTTGTTTATTTAGTAGGCTGCTATTTATAAAGGAAACATACTCATTAGTTGGTCTTTGCGTACATAATGGT
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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