Basic Information
VIS ID
TVIS30000079
Fusion event
HIV-LOC105373108 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
GRCh37/hg19
Start
224990744/224803042 (Hg38)
End
224990744/224803042 (Hg38)
Orient
-
Location type
Inergenic
Fragile sites / regions
FRA1H
Target gene
LOC105373108
Nearest miRNA
hsa-mir-101-1/Upstream/404731; hsa-mir-1182/Downstream/1119038;
Nearest TSS
ENST00000473358/Upstream/36142; ENST00000498360/Downstream/93220;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/184891, chr1-CpG: 60/Downstream/126476
Nearby gene
CNIH3(+62495) ;
Upstream sequence
GAGACAGTATAGAAAATAGAAGAACAGATTGGGATTTGAACAAACcagtggctttcatatgttttctgacatgactcacagtaagaaatatattgcaact
Downstream sequence
ctctatatgtctgtatgtaaatgaaacaaaagtttcagcaaataatacttctattacatgctatgtactctggtccttccatcccaaaccaatccattaa
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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