Basic Information
VIS ID
TVIS30000086
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr6
Cytoband
p21.33
Reference genome
GRCh37/hg19
Start
30478536/30510759 (Hg38)
End
30478536/30510759 (Hg38)
Orient
-
Location type
Inergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-3143/Upstream/3363071; hsa-mir-10398/Downstream/73573;
Nearest TSS
ENST00000381078/Upstream/21247; ENST00000415195/Downstream/5507;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/20361, chr6-CpG: 20/Downstream/44750
Nearby gene
HLA-E(+16554) ;
Upstream sequence
TTCCggctccttggagaaacggtcgattctaggactggggcatcctatgatgtcagaaagtatttacatgctcgattaaaaggtgagaaccatatcaaag
Downstream sequence
ggacacaggagccaactggaaataattccaatagttaaaatggaaacaatttgagcaacaaaataagtaataatggaattggattataacccatagaata
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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