Basic Information
VIS ID
TVIS30000098
Fusion event
HIV-COX10-AS1 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
13956182/14052865 (Hg38)
End
13956182/14052865 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA17A
Target gene
COX10-AS1
Nearest miRNA
hsa-mir-1253/Upstream/509219; hsa-mir-10226/Downstream/1198762;
Nearest TSS
ENST00000595228/Upstream/85913; ENST00000429152/Downstream/16631;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/450623, chr17-CpG: 41/Downstream/16448
Upstream sequence
tcaaattaggacagtgagcagggggtcattatactaatctctctgcctctgtatttgaaattttccataatAAACAGAGGCTGGTGGAAAGTTTTATATG
Downstream sequence
TTCCATAAAGACATTCAATAGTTACAGATGGCTCAGCACCTAGCCAGGACATTAGGAAGTTCCCGCCTCAACCCAGTTGGCCCACAAACACAAACACACA
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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