Basic Information
VIS ID
TVIS30000099
Fusion event
HIV-PPM1G integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
27620334/27397467 (Hg38)
End
27620334/27397467 (Hg38)
Orient
+
Location type
Intronic
Target gene
PPM1G
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-let-7b-5p ; hsa-mir-877-3p ; hsa-mir-484 ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-1301/Upstream/2068746; hsa-mir-10b/Downstream/598900;
Nearest TSS
ENST00000437798/Upstream/16677; ENST00000356442/Downstream/12088;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/3894, chr2-CpG: 105/Downstream/11550
Upstream sequence
aaccagacaaagacatcacaagaaactacagaccaatatctcttatgaatatagacacaaaaatcctcaacaaaatagtagcaaactaaatccagcacca
Downstream sequence
tataaaaggataatacacattgatcaaataagacttatacaccaaaaaaatgcaaggttggtttaacattcaaaaaaatcacttaatgcaatatagcgta
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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