Basic Information
VIS ID
TVIS30000106
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
57935983/59858622 (Hg38)
End
57935983/59858622 (Hg38)
Orient
-
Location type
Inergenic
Nearest miRNA
hsa-mir-10226/Upstream/17285; hsa-mir-1250/Downstream/184403;
Nearest TSS
ENST00000595228/Upstream/20671; ENST00000477179/Downstream/20140;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/150875, chr17-CpG: 73/Downstream/34059
Nearby gene
TUBD1(-858) ;
Upstream sequence
TTGGCTTAACGAAATGCAGCAGCGGGGTGTGCCTTTTAGCAGCAGAACCGACCACTTTTTACATTCCTTACAAATAAGATATGGTTCAGTATTTTAAATC
Downstream sequence
ATAGCAACAGTTGATAAGAAAAACAGCAAAAAGGTAATCATTTCCATATGGAAAGAAAAAGAAGAACCAGTGAAGCTGTGAACTGTCATTTTTCCATATA
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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