Basic Information
VIS ID
TVIS30000107
Fusion event
HIV-RAD54L2 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr3
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
51613329/51579313 (Hg38)
End
51613329/51579313 (Hg38)
Orient
+
Location type
Intronic
Target gene
RAD54L2
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-5581-3p ; hsa-mir-6892-5p ; hsa-mir-4668-5p ; hsa-mir-6077 ; hsa-mir-3135a ; hsa-mir-5584-5p ; hsa-mir-3142 ; hsa-mir-1245b-5p ; hsa-mir-4475 ; hsa-mir-614 ; hsa-mir-7-5p ; hsa-mir-4429 ; hsa-mir-3620-5p ; hsa-mir-1587 ; hsa-mir-377-3p ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-762 ; hsa-mir-5001-5p ; hsa-mir-4498 ; hsa-mir-4492 ; hsa-mir-6829-5p ; hsa-mir-4656 ; hsa-mir-4663 ; hsa-mir-378g ; hsa-mir-342-3p ; hsa-mir-1207-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-129-5p ; hsa-mir-3152-5p ; hsa-mir-4774-3p ; hsa-mir-6836-3p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-653-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6884-3p ; hsa-mir-2053 ; hsa-mir-3941 ; hsa-mir-4719 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-6885-3p ; hsa-mir-3074-5p ; hsa-mir-7162-5p ; hsa-mir-3977 ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-2115-5p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-12127/Upstream/904150; hsa-let-7g/Downstream/688965;
Nearest TSS
ENST00000440867/Upstream/37733; ENST00000462377/Downstream/50078;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/40056, chr3-CpG: 103/Downstream/91733
Upstream sequence
gtgcagcggtgcagtcttggctcactgcaagctccacctcaagcctgggatttttatgggtgcaggatggggggcagggcgggccatgggtggttttgga
Downstream sequence
aaaggaaaacatttgagtgggaaaacagatgtaagttctcactttgggccatggttccaggcttgagggtggggcccttgccagggacctgccctcttct
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
Curate