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TVIS30000109
Basic Information
VIS ID
TVIS30000109
Fusion event
HIV-DHTKD1 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr10
Cytoband
p14
Reference genome
GRCh37/hg19
Start
12155654/12113655 (Hg38)
End
12155654/12113655 (Hg38)
Orient
-
Location type
Intronic
Target gene
DHTKD1
miRNAs that regulate target gene
hsa-mir-1296-5p
;
hsa-mir-92a-3p
;
hsa-mir-16-5p
;
hsa-let-7b-5p
;
hsa-mir-129-5p
;
hsa-mir-1228-5p
;
hsa-mir-6881-5p
;
hsa-mir-6787-5p
;
hsa-mir-663a
;
hsa-mir-1908-5p
;
hsa-mir-7150
;
hsa-mir-4736
;
hsa-mir-4763-3p
;
hsa-mir-1207-5p
;
hsa-mir-4695-3p
;
hsa-mir-4772-3p
;
hsa-mir-6787-3p
;
hsa-mir-1304-3p
;
hsa-mir-6736-3p
;
hsa-mir-6890-3p
;
hsa-mir-4482-3p
;
hsa-mir-7159-3p
;
hsa-mir-1238-3p
;
hsa-mir-670-3p
;
hsa-mir-4753-3p
;
hsa-mir-6873-3p
;
hsa-mir-6881-3p
;
hsa-mir-6780a-3p
;
hsa-mir-7111-3p
;
hsa-mir-130b-5p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-138-2-3p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-6878-3p
;
hsa-mir-640
;
hsa-mir-378a-5p
;
hsa-mir-6778-3p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-3653-5p
;
hsa-mir-150-5p
;
hsa-mir-212-5p
;
hsa-mir-186-3p
;
hsa-mir-6849-3p
;
hsa-mir-764
;
hsa-mir-125a-3p
;
hsa-mir-1226-3p
;
hsa-mir-5585-3p
;
hsa-mir-6783-3p
;
hsa-mir-4279
;
hsa-mir-1343-3p
;
hsa-mir-23b-5p
;
hsa-mir-23a-5p
;
hsa-mir-1976
;
hsa-mir-6742-3p
;
hsa-mir-6852-5p
;
hsa-mir-939-3p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-660-3p
;
hsa-mir-3934-5p
;
hsa-mir-5586-5p
;
hsa-mir-6512-3p
;
hsa-mir-6720-5p
;
hsa-mir-6746-3p
Nearest miRNA
hsa-mir-3155a/Upstream/5961378; hsa-mir-107/Downstream/17105;
Nearest TSS
ENST00000439456/Upstream/19395;
ENST00000479283/Downstream/5124;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/44355
,
chr10-CpG: 101/Downstream/15571
Upstream sequence
TCAATTGTAATGAAGGACAGGGATAGCAGATGTTATACTAGTGCCCTCCTGAGCAGAAATACTATTTAGAAAAGCTTTTAGGCTATTAggctgggcatgg
Downstream sequence
tggctcatgcctataattccaggactttgggaggcctaggcaagaggattgcttgagcccaggagtttgagagcaacctgggcaacattgcaagacccca
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
Sample Information
×
Sample name
Patient2
Sample type
PBMC
Age
55
Gender
Male
CpG Island Information
×
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