Basic Information
VIS ID
TVIS30000115
Fusion event
HIV-chr5 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
131736104/132400412 (Hg38)
End
131736104/132400412 (Hg38)
Orient
-
Location type
Inergenic
Fragile sites / regions
FRA5C
Nearest miRNA
hsa-mir-10397/Upstream/34813; hsa-mir-103a-1/Downstream/1027184;
Nearest TSS
ENST00000502646/Upstream/11452; ENST00000416135/Downstream/10420;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/30172, chr5-CpG: 83/Downstream/10121
Nearby gene
SLC22A5(+4798) ;
Upstream sequence
agacccatcagtgtgctgtattcagaagacctatctcatgagcaaagacatatatattgtctcaaaatgaagggatggaggaagatctaccaagcaaatg
Downstream sequence
gaaaacaaaagcaggggttgcaatcctagtttctgataaaaacagactttaaaccaacaaagatcaaaagaaacaaagaaggccattacataatggtaaa
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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