Basic Information
VIS ID
TVIS30000124
Fusion event
HIV-LINC00298 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
8096042/7955911 (Hg38)
End
8096042/7955911 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC00298
Nearest miRNA
hsa-mir-7158/Upstream/1305472; hsa-mir-10b/Downstream/2236703;
Nearest TSS
ENST00000437798/Upstream/56256; ENST00000442864/Downstream/23399;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/188302, chr2-CpG: 23/Downstream/71981
Upstream sequence
AAATGGAATGAAATTACCCACACTGAGAAGAAAAACTGCCTTCCCTGCTGTGGGTAAGGTAGGCCAGTAAACATGTTTCCACCTTCTGCCACTCCTCCTC
Downstream sequence
CCAGGAAGACAACAAGAAACTATTTTCTACCAAACTGCATGTATTAGATAAAATTTGTTTGCCCATGAGATGAAACACTgcatggtggttaaagcaggga
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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