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TVIS30000129
Basic Information
VIS ID
TVIS30000129
Fusion event
HIV-TMEM245 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr9
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
111848145/109085865 (Hg38)
End
111848145/109085865 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA9E
Target gene
TMEM245
miRNAs that regulate target gene
hsa-mir-374b-5p
;
hsa-mir-340-5p
;
hsa-mir-106b-5p
;
hsa-mir-186-5p
;
hsa-mir-221-3p
;
hsa-mir-21-5p
;
hsa-mir-16-5p
;
hsa-mir-222-3p
;
hsa-mir-183-5p
;
hsa-mir-4662a-5p
;
hsa-mir-3129-3p
;
hsa-mir-5583-5p
;
hsa-mir-93-3p
;
hsa-mir-3692-5p
;
hsa-mir-6507-5p
;
hsa-mir-548a-3p
;
hsa-mir-548e-3p
;
hsa-mir-548f-3p
;
hsa-mir-548ar-3p
;
hsa-mir-5582-3p
;
hsa-mir-548az-3p
;
hsa-mir-374a-5p
;
hsa-mir-20a-5p
;
hsa-mir-526a
;
hsa-mir-523-5p
;
hsa-mir-522-5p
;
hsa-mir-520c-5p
;
hsa-mir-519c-5p
;
hsa-mir-519b-5p
;
hsa-mir-519a-5p
;
hsa-mir-518f-5p
;
hsa-mir-518e-5p
;
hsa-mir-518d-5p
;
hsa-mir-520g-5p
;
hsa-mir-142-3p
;
hsa-mir-4280
;
hsa-mir-562
;
hsa-mir-513c-3p
;
hsa-mir-513a-3p
;
hsa-mir-3606-3p
;
hsa-mir-7844-5p
;
hsa-mir-6864-3p
;
hsa-mir-3672
;
hsa-mir-27b-5p
;
hsa-mir-873-3p
;
hsa-mir-376b-3p
;
hsa-mir-376a-3p
;
hsa-mir-3157-5p
;
hsa-mir-95-3p
;
hsa-mir-4524b-5p
;
hsa-mir-4524a-5p
;
hsa-mir-6801-5p
;
hsa-mir-676-5p
;
hsa-mir-103b
;
hsa-mir-4691-3p
;
hsa-mir-646
;
hsa-mir-503-5p
;
hsa-mir-6838-5p
;
hsa-mir-497-5p
;
hsa-mir-424-5p
;
hsa-mir-195-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-205-3p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-5089-5p
;
hsa-mir-6728-5p
;
hsa-mir-769-3p
;
hsa-mir-450b-3p
;
hsa-mir-6844
;
hsa-mir-6071
;
hsa-mir-593-3p
;
hsa-mir-193a-5p
;
hsa-mir-5187-5p
;
hsa-mir-5589-5p
;
hsa-mir-4731-5p
;
hsa-mir-187-5p
;
hsa-mir-661
;
hsa-mir-4693-3p
;
hsa-mir-9-5p
;
hsa-mir-6728-3p
;
hsa-mir-4686
;
hsa-mir-4712-3p
;
hsa-mir-6512-5p
;
hsa-mir-6793-3p
;
hsa-mir-216b-3p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-4298
;
hsa-mir-1302
;
hsa-mir-3189-3p
;
hsa-mir-212-5p
;
hsa-mir-600
;
hsa-mir-502-5p
;
hsa-mir-6798-3p
;
hsa-mir-4640-3p
;
hsa-mir-361-3p
;
hsa-mir-519d-3p
;
hsa-mir-93-5p
;
hsa-mir-17-5p
;
hsa-mir-20b-5p
;
hsa-mir-1273f
;
hsa-mir-129-5p
;
hsa-mir-193b-5p
;
hsa-mir-19a-5p
;
hsa-mir-19b-1-5p
;
hsa-mir-19b-2-5p
;
hsa-mir-3170
;
hsa-mir-3665
;
hsa-mir-3674
;
hsa-mir-3680-3p
;
hsa-mir-450b-5p
;
hsa-mir-4732-5p
;
hsa-mir-507
;
hsa-mir-557
;
hsa-mir-6511b-5p
;
hsa-mir-6516-5p
;
hsa-mir-657
;
hsa-mir-6811-5p
;
hsa-mir-6832-5p
;
hsa-mir-6855-5p
;
hsa-mir-6890-5p
Nearest miRNA
hsa-let-7a-1/Upstream/39567; hsa-mir-12126/Downstream/425610;
Nearest TSS
ENST00000422679/Upstream/46538;
ENST00000465091/Downstream/1428;
Nearest CpG islands
None/Target,
chr9-CpG: 64/Upstream/72211
,
chr9-CpG: 101/Downstream/33337
Upstream sequence
TACAAACACCTGAGCAAGGAGATACCATCCATATCCTAGACAGCCTTTGCTGAGTTTTTACCAAATTATACTGTGATAGTATTCATGCTTCACAACCTTC
Downstream sequence
CATAGCTTATAATTAAAACTTTGAAAACAAAAACTTAGTTTGACACATGGACAGAAACATAGAGTGAAAAAGGCGATACAGGGGCATTACGGAATTCAAT
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
Sample Information
×
Sample name
Patient2
Sample type
PBMC
Age
55
Gender
Male
CpG Island Information
×
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