Basic Information
VIS ID
TVIS30000130
Fusion event
HIV-ZNF720 integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
31726630/31715309 (Hg38)
End
31726630/31715309 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF720
Nearest miRNA
hsa-mir-1225/Upstream/821324; hsa-mir-11401/Downstream/2448269;
Nearest TSS
ENST00000527434/Upstream/2003; ENST00000561814/Downstream/158449;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/1559, chr16-CpG: 56/Downstream/103977
Upstream sequence
tttggttaacacatattttgttttgaccatcgaagataaaactctttatttaattgcttatgagggggaaaaaaaggaaataggagagtttgtggctttg
Downstream sequence
tgatacctaaaacagggagcatcatctaagtcataacaggaagaagattctttgcagtaagctgctcttgaagaacaaaaaggaagggggatttctttca
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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