Basic Information
VIS ID
TVIS30000133
Fusion event
HIV-chrX integration
Validated
Yes
Detection method
dd-PCR+WGA
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2019
PubMed ID
30688658
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chrX
Cytoband
q28
Reference genome
GRCh37/hg19
Start
153098414/153832959 (Hg38)
End
153098414/153832959 (Hg38)
Orient
+
Location type
Inergenic
Fragile sites / regions
FRAXE ; FRAXF
Nearest miRNA
hsa-let-7f-2/Upstream/497422; hsa-mir-1184-1/Downstream/148138;
Nearest TSS
ENST00000429181/Upstream/2394; ENST00000370049/Downstream/31010;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2077, chrX-CpG: 106/Downstream/52603
Nearby gene
PDZD4(-2392) ;
Upstream sequence
gcttcctgagggttccgcacagcatcctggcctaccatggacagatccctccagcaccgttaggttggcgggctctcgctgctggtggcagagcagcttg
Downstream sequence
ccccgcagcccagtcctcctgcagggtcctttcttgctctggatcccactcaaaacaggTCTCAGTTAgccgggcgtggtggcacgcacctgtagtccca
Reference
Einkauf, K. B., et al. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest,2019, 129(3): 988-998.
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