VISDB Viral Integration Site DataBase

VIS ID

TVIS30000135

Fusion event

HIV-HIF1A integration

Validated

Yes

Detection method

dd-PCR+WGA

Data source

download(RID)

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Normal

Reported year

2019

PubMed ID

Virus name

HIV

Reference genome

Chromosome

chr14

Cytoband

q23.2

Reference genome

Start

End

62172442/61705724 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-20a-5p ; hsa-mir-519c-3p ; hsa-mir-20b-5p ; hsa-mir-107 ; hsa-mir-18a-5p ; hsa-mir-17-5p ; hsa-mir-424-5p ; hsa-mir-199a-5p ; hsa-mir-138-5p ; hsa-mir-199b-5p ; hsa-mir-33a-5p ; hsa-mir-106b-3p ; hsa-let-7b-5p ; hsa-mir-210-3p ; hsa-mir-3121-3p ; hsa-mir-3668 ; hsa-mir-6815-3p ; hsa-mir-589-3p ; hsa-mir-889-3p ; hsa-mir-935 ; hsa-mir-1910-3p ; hsa-mir-3074-3p ; hsa-mir-5094 ; hsa-mir-6511a-5p ; hsa-mir-6755-5p ; hsa-mir-6806-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-519d-3p ; hsa-mir-4282 ; hsa-mir-8055 ; hsa-mir-153-5p ; hsa-mir-18b-5p ; hsa-mir-3662 ; hsa-mir-4735-3p ; hsa-mir-576-3p ; hsa-mir-151a-3p ; hsa-mir-5681b ; hsa-mir-155-5p ; hsa-mir-5692a ; hsa-mir-22-3p ; hsa-mir-21-5p ; hsa-mir-5089-3p ; hsa-mir-4662a-5p ; hsa-mir-1322 ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-6807-3p ; hsa-mir-217 ; hsa-mir-4799-5p ; hsa-mir-4463 ; hsa-mir-4499 ; hsa-mir-329-5p ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-106a-3p ; hsa-mir-299-5p ; hsa-mir-4470 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-3128 ; hsa-mir-625-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-494-3p ; hsa-mir-142-5p ; hsa-mir-27a-3p ; hsa-mir-433-3p ; hsa-mir-429 ; hsa-mir-338-3p ; hsa-mir-186-5p ; hsa-mir-138-1-3p ; hsa-mir-145-5p ; hsa-mir-200c-5p ; hsa-mir-497-3p

Nearest miRNA

hsa-mir-208a/Upstream/1057013; hsa-mir-1185-1/Downstream/2389300;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/9211, chr14-CpG: 43/Downstream/45283

Nearest cancer related gene

HIF1A(TSG, No orient, 0)

Upstream sequence

GCATAGGCCATATTAAAAATGGGGCTTCATATTAAAATGGGGAAAAGGGTGGAGATTCTCAGGTGGAATCTGAGATCTGCCACACACTAATAGTGTTACC

Downstream sequence

TAACCCTTTTTAAAGACAAAGAAACAGGATCAGAAGGTCACTTTGGAAAATTTATTTGGTAATATTGGATAGGATGGATTAGTATAGTTGGAAAACAGAG